A time to fast

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Citation: Andrea Di Francesco, Clara Di Germanio, Michel Bernier, Rafael de Cabo (2018/11/16) A time to fast. Science (RSS)
DOI (original publisher): 10.1126/science.aau2095
Semantic Scholar (metadata): 10.1126/science.aau2095
Sci-Hub (fulltext): 10.1126/science.aau2095
Internet Archive Scholar (search for fulltext): A time to fast
Download: http://science.sciencemag.org/content/362/6416/770


Discuss calorie restriction (CR; daily caloric intake typically decreased 15-40%) and three other strategies which may use some of the same pathways and obtain results akin to CR:

  • time-restricted feeding (TRF; limits daily intake of food to a 4- to 12-hour window)
  • intermittent or periodic full or partial fasting (periodic, full- or multiday decrease in food intake)
  • fasting-mimicking diets (FMDs; maintenance of a physiological fasting-like state by reducing caloric intake and modifying diet composition but not necessarily fasting)